XIAP Regulates Cytosol-Specific Innate Immunity to Listeria Infection
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چکیده
منابع مشابه
XIAP Regulates Cytosol-Specific Innate Immunity to Listeria Infection
The inhibitor of apoptosis protein (IAP) family has been implicated in immune regulation, but the mechanisms by which IAP proteins contribute to immunity are incompletely understood. We show here that X-linked IAP (XIAP) is required for innate immune control of Listeria monocytogenes infection. Mice deficient in XIAP had a higher bacterial burden 48 h after infection than wild-type littermates,...
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ژورنال
عنوان ژورنال: PLoS Pathogens
سال: 2008
ISSN: 1553-7374
DOI: 10.1371/journal.ppat.1000142